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WesternU pharmacy professor receives grant to study

nicotine addiction

Western University of Health
Sciences College of Pharmacy
Professor Kabirullah Lutfy,
PhD, MSci, BPharm, received a College of Pharmacy
$475,000 grant from the
Tobacco-Related Disease Research Highlights over
Research Program (TRDRP) to the past 20 years
study potential treatments for
nicotine addiction.
Dr. Lutfy’s research looks to Dr. Kabir Lufty received the first and
enhance understanding of the largest National Institute of Health
neurosciences of nicotine use (NIH) Award $521,550, “The
and abuse. TRDRP is funded through the Tobacco Tax and Health Protection Act, OFQ/N/ORl-1 receptor system &
approved by California voters in 1988. Cocaine Sensitization,” 2004-2006.
Lutfy has been involved in nicotine research for about four years. Nicotine, the active Dr. Sunil Prabhu received the first
ingredient in tobacco, has both pleasurable and aversive effects, which are known to National Cancer Institutute (NCI)
play a critical role in nicotine addiction. While the rewarding action of nicotine Award $118,450, “Combined
contributes to the initiation of addiction to it, the aversive effect of nicotine hampers its Chemoprevention Using a
initial use and helps some people not to become addicted. Nanotechnology based Therapeutic
System,” 2007-2010.
Earlier this year, Lutfy and his collaborators from Cornell University, the University of
Pennsylvania, and Columbia University published a paper in Nature. Dr. Kabir Lutfy has been awarded
the highest overall in grants (NIH
and Non NIH) for a total of
WesternU researcher explores link between diabetes, $1,394,197.00

pleasurable effects of nicotine Dr. Ying Huang has been awarded
the most non NIH grants for a of
Western University of Health total of $1,156,086.81
Sciences’ College of Pharmacy
Associate Professor
Arbi Nazarian, PhD, received a The Pharmacy Practice and
$446,000 grant from the
National Institutes of Health Administration Faculty grants over
(NIH) to investigate how the $100,00 were:
pleasurable effects of nicotine Dr. James Scott: $144,411, “Open
are altered in persons with Label, Multiple Dose, Drug
diabetes. Interaction Study,” Bristol-Meyers

Nazarian’s study, titled “Insulin Squibb, 2005-2006.
mechanism of diabetes-evoked Dr. Sam Shimomura: $141,565,
enhancement of nicotine reward, “combines two health conditions – diabetes and Partners in D, Amgen Foundation,
nicotine/smoking. 2007-2011.

The long-term goal is to identify ways by which control and treatment of metabolic Dr. Moses Chow: $102,126, Pre-
disorders can assist in facilitating nicotine cessation in persons who smoke and are clinical evaluation of sublingual and
diabetic. transmucosal delivery if PGE1,
Nazarian and his collaborator, Dr. Laura O’Dell, Associate Professor of Psychology at Rexan Pharmaceutical, 2011-2012
the University of Texas at El Paso (UTEP), hope their findings from the project help Dr. Cynthia Jackevcius: $140,000,
define neurobiological mechanisms by which persons with diabetes have a greater Adherence to atrial fibrillation
vulnerability to tobacco use. therapies, AHA, 2012-2014.



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